Table 3 Significantly Up-Regulated Proteins in IAPP Treated Rin-5F Cells. The data were obtained from three independent experiments. To obtain the protein abundance ratio the amount of each protein in the IAPP treated cells was divided by its corresponding amount in the control cells (IAPP untreated cells). The corresponding ratios of all proteins were then averaged between the three experiments. If a specific protein was expressed in either untreated or IAPP treated samples, the missing value was replaced by the smallest amount that was potentially detected by the machine (0.1 femtomole). Differences between IAPP treated and un-treated expression levels are considered to be significant if p ≤ 0.05. To determine the p value two-tailed Student’s t-test was performed, comparing the three individual control amounts with the three corresponding treated samples

From: Effect of IAPP on the proteome of cultured Rin-5F cells