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Fig. 3 | BMC Biochemistry

Fig. 3

From: Identification and characterization of smallest pore-forming protein in the cell wall of pathogenic Corynebacterium urealyticum DSM 7109

Fig. 3

Analysis of the accessible genomes from C. glutamicum (ATCC 13032), C. efficiens (YS-314 DNA), C. diphtheriae (NCTC 13129), C. jeikeium (K411) and C. urealyticum (DSM 7109). The homologous genes of the chaperonin GroEL2 and a polyphosphate kinase PPK2 enclose a presumed conserved porin domain. The operon covering the genes CgporH and CgporA whose gene products form the main cell wall channel of C. glutamicum is assumed to exist in all strains except for C. jeikeium. Search within the genome of C. urealyticum indicated that this strain does not follow this rule and suggested instead that it contained 3 open reading frames (ORFs) between the genes coding for GroEL2 (cur_1716) and PKK2 (cur_1712). They may code for cell wall proteins similar to PorA. Possible terminator sequences of mRNA transcripts were predicted with TranstermHP (indicated by hairpins [78] or were identified manually (marked by asterisk))

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