Table 3 Structural parameters derived from experimental SAXS data and comparison to known parameters of mouse CNPase

D _max (nm)

11.6

14.3

8.5

8.8

7.1

Guinier R _g (nm)

3.37

4.16

2.48

2.6

2.13

Real-space R _g (nm)

3.79

4.83

2.69

-

-

V_P (nm³)

78.6

137.7

50.1

-

44.4

Ab initio V (nm³)/estimated MW of globular particle (kDa)

106/78.7

212/157.4

30.5/22.6

-

-

Monomeric MW (kDa)

52.7

60.3

32.2

42

24

s_min/s_max (nm⁻¹) bead-based modeling

0.09-2.52

0.12-1.31

0.08-3.72

-

-

s_min/s_max (nm⁻¹) chain-based modeling

0.09-5.0

0.12-2.8

0.08-3.72

-

-

Chi²

1.0 (DAMMIF), 0.7 (GASBOR), 1.3 (MONSA)

1.0 (DAMMIF), 1.0 (GASBOR)

0.6 (DAMMIF), 0.7 (GASBOR), 1.2 (MONSA)

-

-