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Fig. 9 | BMC Biochemistry

Fig. 9

From: Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor

Fig. 9

Comparison of PTP1B and DUSP5 PD. a Structural overlay of PTP1B and DUSP5 PD(WT), based on crystal structures with pdb codes 3CWE (PTP1B with a phosphonic acid inhibitor bound) and 2G6Z (DUSP5 PD), using Chimera. b Primary sequence alignment was done using Clustal Omega pairwise alignment and guide tree algorithm [37], which indicated an extremely low percent identity of 9.5%

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BMC Biochemistry

ISSN: 1471-2091

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