Fig. 6From: Effects of protonation on the hydrolysis of triphosphate in vacuum and the implications for catalysis by nucleotide hydrolyzing enzymesEffect of protonation on the two steps of the sequential mechanism. Energy barriers a ΔE 1 ǂ for breaking the Pγ-Oβγ bond and b ΔE 2 ǂ for breaking of water Wa (as given in Table 2). Greek letters (α,β,γ) indicate on which phosphate the proton is located (for example αγ means αγ-protonation). Zero means that there are no protons on the triphosphate (nP = 0)Back to article page