Fig. 3
From: Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity
Time courses of methylation of oligodeoxynucleotide duplex by wt or Dnmt3a-CD variants. a The reaction mixtures contained 1.5 μM GC GC/CG CG, 0.89 μM Dnmt3a-CD or its variants, and 2 μM [CH3-3H]AdoMet. b Relative initial methylation rates (v 0 rel,%) for wt and Dnmt3a-CD variants. The error bars represent the SDs derived from at least three independent experiments