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Figure 7 | BMC Biochemistry

Figure 7

From: Importance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B

Figure 7

Autoradiographs showing GrB induced cleavage of combined primed site hBNIP-2 variants. In vitro transcribed and translated combined hBNIP-2 variants were incubated with varying concentrations (ranging from 3.9 nM to 1 μM (from left to right)) of human and mouse GrB. Black arrows indicate BNIP-2 precursor patterns whereas dashed and grey arrows are indicative for BNIP-2 cleavage fragments. Percentages of cleavage are shown in the progression curves of hGrB and mGrB cleavage and indicated by full and dashed lines respectively.

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BMC Biochemistry

ISSN: 1471-2091

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